SPARQL example query

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drosophila_enzymes_derived_from_at_least_two_mRNAs: Find Drosophila proteins, that depend on more than one transcript (requires cross-references to Ensembl family of resources).

PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#> PREFIX taxon: <http://purl.uniprot.org/taxonomy/> PREFIX up: <http://purl.uniprot.org/core/> SELECT ?protein WHERE { ?protein up:organism taxon:7227 ; a up:Protein ; up:reviewed true ; rdfs:seeAlso ?transcript . ?transcript a up:Transcript_Resource . } GROUP BY ?protein HAVING(COUNT(?transcript) >= 2)Use

drosophila_proteins_derived_from_at_least_two_mRNAs: Find Drosophila enzymes, that depend on more than one transcript (requires cross-references to Ensembl family of resources).

PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#> PREFIX taxon: <http://purl.uniprot.org/taxonomy/> PREFIX up: <http://purl.uniprot.org/core/> SELECT ?protein WHERE { ?protein up:organism taxon:7227 ; a up:Protein ; up:reviewed true ; rdfs:seeAlso ?transcript . { ?protein up:annotation/a up:Catalytic_Activity_Annotation ; } UNION { ?protein up:enzyme ?enzyme . } ?transcript a up:Transcript_Resource . } GROUP BY ?protein HAVING(COUNT(?transcript) >= 2)Use

enzyme_with_threonine_as_active_site: Find enzymes with a Tyrosine (Y) as an active site

PREFIX faldo: <http://biohackathon.org/resource/faldo#> PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> PREFIX up: <http://purl.uniprot.org/core/> SELECT ?protein WHERE { ?protein up:annotation ?activeSiteAnnotation . ?activeSiteAnnotation a up:Active_Site_Annotation ; up:range ?range . ?range faldo:begin ?begin . ?begin faldo:position ?beginPosition ; faldo:reference ?sequence . ?sequence rdf:value ?sequenceVal . FILTER(SUBSTR(?sequenceVal, ?beginPosition, 1) = 'Y') }Use

uniprot_encoding_gene_name_alternative_name: List UniProtKB proteins with their associated gene and the gene's names that are used in the field, but not recommended for use by UniProtKB

PREFIX skos: <http://www.w3.org/2004/02/skos/core#> PREFIX up: <http://purl.uniprot.org/core/> SELECT ?protein ?gene ?altGeneName WHERE { ?protein a up:Protein ; up:encodedBy ?gene . ?gene skos:altLabel ?altGeneName . }Use
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