| http://purl.uniprot.org/citations/16142217 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16142217 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16142217 | http://www.w3.org/2000/01/rdf-schema#comment | "Unlike other positive-stranded RNA viruses that use either a 5'-cap structure or an internal ribosome entry site to direct translation of their messenger RNA, calicivirus translation is dependent on the presence of a protein covalently linked to the 5' end of the viral genome (VPg). We have shown a direct interaction of the calicivirus VPg with the cap-binding protein eIF 4 E. This interaction is required for calicivirus mRNA translation, as sequestration of eIF 4 E by 4 E-BP 1 inhibits translation. Functional analysis has shown that VPg does not interfere with the interaction between eIF 4 E and the cap structure or 4 E-BP 1, suggesting that VPg binds to eIF 4 E at a different site from both cap and 4 E-BP 1. This work lends support to the idea that calicivirus VPg acts as a novel 'cap substitute' during initiation of translation on virus mRNA."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.embor.7400510"xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.embor.7400510"xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16142217 |
| http://purl.uniprot.org/citations/16142217 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16142217 |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Roberts L."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Roberts L."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Goodfellow I."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Goodfellow I."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Chaudhry Y."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Chaudhry Y."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Laliberte J.F."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Laliberte J.F."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Gerondopoulos A."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Gerondopoulos A."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Gioldasi I."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Gioldasi I."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Labrie L."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Labrie L."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Natoni A."xsd:string |
| http://purl.uniprot.org/citations/16142217 | http://purl.uniprot.org/core/author | "Natoni A."xsd:string |