http://purl.uniprot.org/citations/17300186 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17300186 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17300186 | http://www.w3.org/2000/01/rdf-schema#comment | "The Ras/Raf/MEK/ERK signal transduction is a key oncogenic pathway implicated in a variety of human cancers. We have identified a novel series of pyrazolylpyrroles as inhibitors of ERK. Aided by the discovery of two distinct binding modes for the pyrazolylpyrrole scaffold, structure-guided optimization culminated in the discovery of 6p, a potent and selective inhibitor of ERK."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/name | "J. Med. Chem."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/name | "J. Med. Chem."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.org/dc/terms/identifier | "doi:10.1021/jm061381f"xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.org/dc/terms/identifier | "doi:10.1021/jm061381f"xsd:string |
http://purl.uniprot.org/citations/17300186 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17300186 |
http://purl.uniprot.org/citations/17300186 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17300186 |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Cao J."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Cao J."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Chen G."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Chen G."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Baker C."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Baker C."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Tang Q."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Tang Q."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Xie X."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Xie X."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Green J."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Green J."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Jacobs M."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Jacobs M."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Straub J."xsd:string |
http://purl.uniprot.org/citations/17300186 | http://purl.uniprot.org/core/author | "Straub J."xsd:string |