http://purl.uniprot.org/citations/8509423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8509423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8509423 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified and purified a new DNA binding protein, designated HDF (high affinity DNA-binding factor) from Saccharomyces cerevisiae. HDF binds in a sequence-independent manner to the ends of double-stranded DNA. The protein appears as a stable heterodimer of two polypeptides with molecular masses of 70 and 85 kDa. We have cloned and sequenced the 70-kDa subunit of the HDF protein. The amino acid sequence shows a weak but significant homology with the p70 subunit of the human Ku autoantigen, a protein that also binds to the ends of double-stranded DNA. Hdf-strains generated by one-step gene disruption show a temperature-sensitive phenotype for growth at 37 degrees C. Cells arrest growth at 37 degrees C and after several hours appear as enlarged single-budded cells with abnormally high DNA content indicating a defect in the regulation of DNA replication coupled with or causing a cell cycle arrest in G2 or mitosis."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)31470-4"xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)31470-4"xsd:string |
http://purl.uniprot.org/citations/8509423 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8509423 |
http://purl.uniprot.org/citations/8509423 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8509423 |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/author | "Feldmann H."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/author | "Feldmann H."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/author | "Winnacker E.L."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/author | "Winnacker E.L."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/pages | "12895-12900"xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/pages | "12895-12900"xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/title | "A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/title | "A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae."xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/volume | "268"xsd:string |
http://purl.uniprot.org/citations/8509423 | http://purl.uniprot.org/core/volume | "268"xsd:string |
http://purl.uniprot.org/citations/8509423 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8509423 |
http://purl.uniprot.org/citations/8509423 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8509423 |
http://purl.uniprot.org/uniprot/#_P32807-citation-8509423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8509423 |
http://purl.uniprot.org/uniprot/#_Q04437-citation-8509423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8509423 |