http://purl.uniprot.org/citations/9647754 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9647754 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9647754 | http://www.w3.org/2000/01/rdf-schema#comment | "In the primary structure of bilitranslocase, currently under study in our laboratory, an aminoacid motif was identified and found to be conserved in a number of alpha-phycocyanines, ancient biliproteins present in cyanobacteria. To test the possibility that such a motif could be at least part of the binding site for bilirubin, epitope-specific antibodies were raised. The target corresponds to the sequence 65-75 of bilitranslocase and covers the central portion of the motif identified. The antibodies were shown: 1) to inhibit the electrogenic BSP transport by plasmamembrane vesicles; 2) to react with purified bilitranslocase; and 3) to identify only one protein band with electrophoretic mobility identical to bilitranslocase in Western blots of solubilised plasmamembrane vesicles. The presence of either bilirubin or nicotinate during pre-incubation with the antibodies decreases concentration-wise the inhibition kinetics. From these experiments a dissociation constant of 2.2 +/-0.3 and 11.3 +/-1.3 nM for bilirubin-bilitranslocase and nicotinate-bilitranslocase complexes were calculated."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1998.8868"xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1998.8868"xsd:string |
http://purl.uniprot.org/citations/9647754 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9647754 |
http://purl.uniprot.org/citations/9647754 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9647754 |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/author | "Macagno A."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/author | "Macagno A."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/author | "Battiston L."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/author | "Battiston L."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/author | "Passamonti S."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/author | "Passamonti S."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/author | "Sottocasa G.L."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/author | "Sottocasa G.L."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/pages | "687-692"xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/pages | "687-692"xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/title | "The bilirubin-binding motif of bilitranslocase and its relation to conserved motifs in ancient biliproteins."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/title | "The bilirubin-binding motif of bilitranslocase and its relation to conserved motifs in ancient biliproteins."xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/volume | "247"xsd:string |
http://purl.uniprot.org/citations/9647754 | http://purl.uniprot.org/core/volume | "247"xsd:string |