http://purl.uniprot.org/citations/9865700 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9865700 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9865700 | http://www.w3.org/2000/01/rdf-schema#comment | "Microtubule-dependent motor, murine KIF3B, was disrupted by gene targeting. The null mutants did not survive beyond midgestation, exhibiting growth retardation, pericardial sac ballooning, and neural tube disorganization. Prominently, the left-right asymmetry was randomized in the heart loop and the direction of embryonic turning. lefty-2 expression was either bilateral or absent. Furthermore, the node lacked monocilia while the basal bodies were present. Immunocytochemistry revealed KIF3B localization in wild-type nodal cilia. Video microscopy showed that these cilia were motile and generated a leftward flow. These data suggest that KIF3B is essential for the left-right determination through intraciliary transportation of materials for ciliogenesis of motile primary cilia that could produce a gradient of putative morphogen along the left-right axis in the node."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81705-5"xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81705-5"xsd:string |
http://purl.uniprot.org/citations/9865700 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9865700 |
http://purl.uniprot.org/citations/9865700 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9865700 |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Harada A."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Harada A."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Kanai Y."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Kanai Y."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Okada Y."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Okada Y."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Takeda S."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Takeda S."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Tanaka Y."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Tanaka Y."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Kido M."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Kido M."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Nonaka S."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Nonaka S."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Hirokawa N."xsd:string |
http://purl.uniprot.org/citations/9865700 | http://purl.uniprot.org/core/author | "Hirokawa N."xsd:string |